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plasminogen

Definitions

  • WordNet 3.6
    • n plasminogen an inactive form of plasmin that occurs in plasma and is converted to plasmin by organic solvents
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Usage


In news:

Studies Provide Structural Insights on Activation, Conversion of Plasminogen to Plasmin.
Approval of recombinant tissue plasminogen activator (alteplase) as an intravenous thrombolytic therapy is currently limited to a 3 h time window after stroke onset.
Studies Provide Structural Insights on Activation, Conversion of Plasminogen to Plasmin .
Studies Provide Structural Insights on Activation, Conversion of Plasminogen to Plasmin.
Administering a clot-dissolving experimental drug known as TPA (tissue plasminogen activator) directly into the brain may help to stop a stroke in progress, according to Phillip A Scott, M.D.
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In science:

Clark W. M., Wissman S., Albers G. W., Jhamandas J. H., Madden K. P. and Hamilton S. (1999) Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset.
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
Pharmacol. 330 (1997) 221-229. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group, Tissue plasminogen activator for acute ischemic stroke, New England J.
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat
Postischemic (6-Hour) treatment with recombinant human tissue plasminogen activator and proteasome inhibitor PS-519 reduces infarction in a rat model of embolic focal cerebral ischemia.
Neuroprotective efficacy of nimesulide against hippocampal neuronal damage following transient forebrain ischemia
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