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antibody

Definitions

  • WordNet 3.6
    • n antibody any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
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Webster's Revised Unabridged Dictionary
    • Antibody (Med., Physiol. Chem) Any of various bodies or substances in the blood which act in antagonism to harmful foreign bodies, as toxins or the bacteria producing the toxins. Normal blood serum apparently contains various antibodies, and the introduction of toxins or of foreign cells also stimulates production of their specific antibodies by the immune system.
    • Antibody (Med., Physiol. Chem) more narrowly, any of the immunoglobulins present in the blood serum or other body fluids of an animal, which reacts with a specific antigenic substance, whether the antibody was produced as a consequence of the stimulus provided by the antigen, or was pre-existing prior to exposure of the organism to the antigen.
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Century Dictionary and Cyclopedia
    • n antibody A body or substance which inhibits the action of another substance. Also called antisubstance and, as a general term, adaptation-product. See adaptation-product and immunity.
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Usage

In literature:

When the antibody was analyzed by those techniques of microanalysis the Service had developed, that was that.
"This World Is Taboo" by Murray Leinster
If this is a virus infection, we might only need to find an antibody for inoculation to stop it in its tracks.
"Star Surgeon" by Alan Nourse
Thoreau is suggestive of those antibodies which modern science makes so much of.
"The Last Harvest" by John Burroughs
Here, the blood has no reason to build antibodies.
"Badge of Infamy" by Lester del Rey
Complement is obtained (unmixed with antibody) by collecting fresh blood serum from any healthy normal (that is uninoculated) animal.
"The Elements of Bacteriological Technique" by John William Henry Eyre
The antibody could be synthesized and one could attack any epidemic with confidence.
"Pariah Planet" by Murray Leinster
Only the next time the antibody curve rises, it will be for keeps.
"Category Phoenix" by Boyd Ellanby
Recent studies seem to show that in the animal body fats serve an important function in connection with the production of antibodies to disease germs.
"The Chemistry of Plant Life" by Roscoe Wilfred Thatcher
I'm beginning to wonder if using her to try to create telomerase antibodies is actually such a good idea.
"Syndrome" by Thomas Hoover
Composition of blood, red and colorless corpuscles, plasma, blood plates, antibodies.
"A Civic Biology" by George William Hunter
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In news:

Seattle Genetics and OBT Establish Cancer Antibody-Drug Conjugate Collaboration.
I think that the recent emergence of biologics (antibodies and peptides ) as successful drugs in a variety of fields will open the floodgates for novel therapeutic approaches.
Pinkeye vaccines stimulate the production of antibodies in tears that bathe the eye.
Oral fluid sampling for health monitoring of swine pathogens provides an easy and inexpensive method to test herds for antibodies to the porcine reproductive and respiratory syndrome (PRRS) virus and potentially other diseases.
The complex structure of ADCs necessitates different analytical strategies than those for either small molecules or unconjugated monoclonal antibodies.
AZTV7/Cable 13, Me-TV 7.2, RTV 7.3, Phoenix-Prescott, AZCancer Antibodies: Drug Target Atlas and Competitive Outlook.
(B) Images in the FITC channel of beads coated to capture human IgG: A dilution series of IgG concentration was incubated with the beads, as well as a FITC-labelled capture antibody.
GeneTex Inc, a leading manufacturer of antibodies and antibody-related reagents, will be attending the annual meeting of the America Society for Cell Biology (ASCB) from December 15-19 in San Francisco, CA.
The hCoV-EMC virus could still enter bat cells (blue) even when the ACE2 receptor was blocked by antibodies (red).
Known as T-DM1-, it combines the antibody Herceptin with a chemotherapy agent to seek out cancerous cells.
The University of Texas MD Anderson Cancer Center and GlaxoSmithKline (GSK) have signed a research collaboration and license agreement to develop new therapeutic antibodies that promote an immune system attack against cancer.
Lamprey Antibodies Snag Sugars Linked To Cancer.
SBV antibodies have been discovered in three cows and one calf.
Nixon said the treatment uses the strategy of immunotherapy, a generic approach which introduces an antibody into a patient to try to neutralize a factor that is important for the disease 's progression.
The disks contain commercially available reagents and antibodies specific to each protein marker.
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In science:

All of these are symmetrical. If the variable region of an antibody recognizes a complementary variable region, the latter also recognizes the former. This aspect of the theory is called “first symmetry”.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
Stimulatory interactions involve cross-linking of the specific receptors of lymphocytes. The lymphocytes that make antibodies are called B cells.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
Symmetry in stimulation means for example that if antibodies made by a B cell “Y” are able to cross-link the receptors on a B cell “Z”, thus stimulating the cell, then the antibodies made by the B cell “Z” are likewise able to cross-link the receptors of the B cells “Y”.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
Antibodies have a molecular weight of about 150,000 daltons or more, and are able to cross-link receptors because each antibody has two or more V regions.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
The cross-linking of surface immunoglobulin is a necessary but not sufficient condition for switching on B cells to secrete antibody.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
Tabs have a molecular weight of about 50,000 daltons, from which it is plausible that, in contrast to antibodies, they have only one V region.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
The model of Figure 1 refers to the repertoire of serum IgG antibodies and of the B cells that are co-selected to secrete IgG.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
IgG population, with associated changes in the Ts2 repertoire. The two major classes of antibody in serum are IgM and IgG. Interaction matrices between IgM monoclonal antibodies derived from neonates have been measured16 and found to have a connectance (fraction of non-zero terms) of about 0.2.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
Small doses of IVIG given to humans in immunogenic form via an immunogenic route, for example intra-muscularly, are predicted to induce antiHIV antibodies.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
Med. 154, 1838-1851 (1981). 5. Tada, T., Takemori, T., Okumura, K., Nonaka, M., Tokuhisa, T. Two distinct types of helper T cells involved in the secondary antibody response: Independent and synergistic effect of Ia- and Ia+ helper T cells. J.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
IgM antibodies induce the production of antibodies of the same specificity. Proc.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
Similar idiotype specificities in immunoglobulin fractions with different antibody functions or even without detectable antibody function.
Recent Developments in Immune Network Theory including a concept for an HIV Vaccine
Many biomolecules such as proteins, antibodies and enzymes have natural domains or partitions and can be modeled as a sequence of length L divided into several blocks .
Extreme value distributions for weakly correlated fitnesses in block model
Such nonindependent variables may describe diverse quantities such as breeding value of an animal [26, 27], fitness of a protein or antibody and energy of a directed polymer .
Extreme value distributions for weakly correlated fitnesses in block model
Antibodies to cowpox virus were detected by immunofluorescence assay (see Chantrey et al. (1999)). A brief description of the observed and derived variables is given in Table 1.
A coupled hidden Markov model for disease interactions
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